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US 2012/0231996 A1Published application
Phalloidin derivatives and methods for their synthesis
OwnerR. Scott Lokey, Laura A. Schureskoinventors
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Abstract
The invention provides a cyclomonomer having actin-binding activity. The cyclomonomer is of utility for the study of the molecular biology of actin polymerization. The cyclomonomer is also useful for the study of and treatment of the toxic effects of Amanita sp. poisoning.
Claims15
A cyclomonomer having actin binding activity, the cyclomonomer comprising a heptapeptide having a cystyl residue, a prolyl residue, and a tryptophanyl residue and wherein the cystyl residue and the tryptophanyl residue are linked by a thioester bond.
Dependencies are inferred from the claim text.