Reversing autonomic nervous system dysfunction by potentiating methylation

A method for reversing stress-induced dysfunctions of a human autonomic nervous system in accordance with Methylation Priority Principle and Arginine Priority Principle comprising:

• repeatedly administering a methylation-promoting composition, being composed to promote a hierarchy of methylation functions of the Methylation Priority Principle including uninterrupted methylation cycle recycling of homocysteine to methionine, and uninterrupted processing and removal of metabolic products of stress, the methylation-promoting composition including:
• a first compound chosen from a group of compounds consisting of folic acid, folates, folinic acid, folinates, dihydrofolate, methyltetrahydrofolate and their mixtures and combinations;
• a second compound chosen from a group of compounds consisting of hydroxocobalamin, aquacobalamin, glutathionylcobalamin, adenosylcobalamin and their mixtures and combinations;
• and
• a third compound chosen from a group of compounds consisting of arginin, 1-arginin, ornithine, 1-ornithine, malate salts of arginin and ornithine, and their mixtures and combinations;
• and
• wherein the first compound and the second compound are arranged for a substantially simultaneous administration and administered transbuccally using multiple unit doses to directly enter a human body circulation for substantially simultaneous elevations of a tissue concentration of the first compound, a tissue concentration of the second compound, and a tissue concentration of the third compound;
• and
• wherein, the methylation-promoting composition is composed as being free of preservatives or excipients that affect diuresis, and preservatives, or excipients that directly effect the human autonomic nervous system.

A methylation-promoting composition for reversing stress-induced dysfunctions of a human autonomic nervous system in accordance with Methylation Priority Principle comprising:

• the methylation-promoting composition arranged to promote a hierarchy of methylation functions of the Methylation Priority Principle including uninterrupted methylation cycle recycling of homocysteine to methionine, and uninterrupted processing and removal of metabolic products of stress, the methylation-promoting composition including:
• a first compound chosen from a group of compounds consisting of folic acid, folates, folinic acid, folinates, dihydrofolate, methyltetrahydrofolate and their mixtures and combinations;
• and
• a second compound chosen from a group of compounds consisting of hydroxocobalamin, aquacobalamin, glutathionylcobalamin, adenosylcobalamin and their mixtures and combinations;
• wherein the first compound and the second compound are arranged for a substantially simultaneous administration and administered transbuccally using multiple:
• unit doses to directly enter a human body circulation for substantially simultaneous elevations of a tissue concentration of the first compound and a tissue concentration of the second compound, and
• wherein, the methylation-promoting composition is composed as being free of preservatives or excipients that affect diuresis, and preservatives, or excipients that directly effect the human autonomic nervous system.