Preventives/remedies for cancer
AssigneeTakeda Pharmaceutical Company Limited
InventorsToshimitsu Arai, Yoshio Taniyama, Toshio Kokubo
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Abstract
The present invention provides a drug containing a substance that inhibits a function of RET, such as an antibody against RET. In addition, the present invention provides a drug containing a substance that inhibits a function of GDNF, such as an antibody against GDNF. Moreover, the present invention provides a drug containing a substance that inhibits a function of GFRα1, such as an antibody against GFRα1. The drug of the present invention is useful as an agent for the prophylaxis or treatment of breast cancer and the like, an inhibitor of cancer cell growth and the like.
Claims15
-84. (canceled)
A method for the prophylaxis or treatment of cancer, comprising administering, to a mammal, an effective amount of an antibody to a protein comprising the same or substantially the same amino acid sequence as that of SEQ ID NO:
- 1 or SEQ ID NO:
- 3, or a partial peptide thereof, or a salt thereof.
A method for inhibiting growth of a cancer cell, comprising administering, to a mammal, an effective amount of an antibody to a protein comprising the same or substantially the same amino acid sequence as that of SEQ ID NO:
- 1 or SEQ ID NO:
- 3, or a partial peptide thereof, or a salt thereof.
Dependencies are inferred from the claim text.