Truncated cystine-knot proteins

Proteinmimic of a member of the cystine-knot growth factor superfamily, said proteinmimic having the motif X0-C1-X1-C2-X2-C3-X3-C4-X4-C5-X5-C6-X6 (SEQ ID NO:2), wherein C1 to C6 are cysteine residues that form a cystine-knot structure in which C1 is linked to C4, C2 is linked to C5 and C3 is linked to C6, and wherein X0 and X6 represent, independently from each other, an amino acid molecule with a length of 0 to 10 amino acids, X2 represents an amino acid molecule with a length of 2 to 24 amino acid residues with at least 70% sequence identity to the amino acid molecule located between C2 and C3 of a member of the cystine-knot growth factor superfamily, X5 represents an amino acid molecule with a length of 1 amino acid residue, X1 represents an amino acid molecule with a length of 15 to 50 amino acids with at least 70% sequence identity to the amino acid molecule located between C1 and C2 of a member of the cystine-knot growth factor superfamily, X3 represents an amino acid molecule with a length of 3 to 36 amino acids with at least 70% sequence identity to the amino acid molecule located between C3 and C4 of a member of the cystine-knot growth factor superfamily, and X4 represents an amino acid molecule with a length of 15 to 50 amino acids with at least 70% sequence identity to the amino acid molecule located between C4 and C5 of a member of the cystine-knot growth factor superfamily.