Targeted particles and methods of using the same
AssigneeThe Trustees of the University of Pennsylvania
InventorsDavid B. Weiner, Karuppiah Muthumani, Donghui Zhang, Mathura P. Ramanathan
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Abstract
Drug delivery compositions and methods of delivering compounds are disclosed. Vaccines and methods of immunizing individuals are disclosed. Compositions for drug delivery including gene therapy and methods of treating individuals using such compositions are disclosed.
Claims24
A method of introducing a compound into a cell that expresses Flt3 molecules, said method comprising contacting the cell with a non-cellular particle that comprises the compound and a Flt-3 ligand.
4-9. (canceled)
11-14. (canceled)
A non-cellular particle that comprises a fusion protein comprising Flt-3 ligand or a FLT-3 binding fragment thereof.
20-24. (canceled)
27-28. (canceled)
35-57. (canceled)
A method of introducing a compound into a cell that expresses a target molecule, said method comprising contacting the cell with a particle that comprises gp41 linked to a ligand that binds to said target molecule.
A particle that comprises a fusion protein comprising gp41 linked to a ligand that binds to said target molecule.
Dependencies are inferred from the claim text.