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US 2012/0180145 A1Published application
Tool for Studying Endothelial Haematopoietic Transition (EHT) and Epithelial-Mesenchymal Transition (EMT) Associated Events
AssigneeAzelead
InventorsKarima Kissa-Marin, Philippe Herbomel
Life of this patent
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Abstract
The present invention relates to the field of endothelial haematopoietic transition (EHT) and epithelial-mesenchymal transition (EMT) and more particularly relates to the use of fish embryo or larva as a model for the study of EHT and EMT.
Claims20
A method for the study of endothelial haematopoietic transition (EHT) or epithelial mesenchymal transition (EMT) comprising the use of a fish embryo or larva as a model for EHT or EMT.
A method for screening for a candidate compound that modulates the endothelial haematopoietic transition (EHT) or epithelial-mesenchymal transition (EMT) mechanism, comprising the steps of:
- introducing a candidate compound into a fish embryo or larva and evaluating the capacity of said candidate compound to modulate the EHT or EMT mechanism, said modulation being an EHT or an EMT inhibitory effect or an EHT or an EMT inducing effect.
Dependencies are inferred from the claim text.