Signature Of Secreted Protein Isoforms Specific To Ovarian Cancer
AssigneeSocpra Sciences Sante Et Humaines S.E.C.
InventorsPanagiotis Prions, Julian Venables, Benoit Chabot, Sherif Abou Elela
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Abstract
The present invention relates to the identification of secreted protein isoforms specific in ovarian cancer and methods for diagnosis or prognosis of ovarian cancer in a subject by detecting the secreted protein isoforms.
Claims64
A method for diagnosis or prognosis of ovarian cancer in a subject by detecting a signature of at least one secreted protein isoform comprising the steps of:
- a) obtaining a sample from said subject, and
- b) determining whether the sample from step a) contains the signature specific to ovarian cancer,
- wherein the presence of the signature is indicative of the presence of ovarian cancer in the individual or the progression of ovarian cancer in the individual.
A diagnostic or prognostic kit for ovarian cancer for detecting a signature of at least one secreted protein isoform in a sample of a subject, said kit comprising:
- a) a moiety that specifically recognized the at least one secreted protein isoform or a mRNA encoding the at least one secreted protein isoform of the signature;
- and
- b) a set of instructions for using said moiety to detect the signature specific to ovarian cancer.
A method for profiling an ovarian cancer in a subject by detecting a signature of at least one secreted protein isoform comprising the steps of:
- a) obtaining a sample from said subject, and
- b) determining whether the sample from step a) contains the signature specific to ovarian cancer.
Dependencies are inferred from the claim text.