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US 2012/0086995 A1Published application
Light microscope with novel digital method to achieve super-resolution
AssigneeWavefront Analysis, Inc.
InventorsRalph W. Gerchberg, Louise Gerchberg
Life of this patent
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Abstract
Methods and apparatus for reconstructing a wave, including interpolation and extrapolation of the phase and amplitude distributions, with application to imaging apparatus, such as microscopes.
Claims5
An apparatus for reconstructing a wave, comprising:
- a source of electromagnetic radiation;
- a specimen located at an output plane and illuminated by the source;
- a detector located at a diffraction plane having a conjugate relationship to the output plane, the detector measuring the amplitude of a wave of the electromagnetic radiation at a first set of points in the diffraction plane;
- and
- a processor estimating the amplitude and phase of the wave at a second set of points in the diffraction plane, wherein at least some of the second set of points are different than the first set of points.
2 more elements
A method for reconstructing a wave, comprising the steps of:
- illuminating a specimen at an output plane;
- measuring at a diffraction plane the amplitude distributions of a number N of diffraction patterns, each of the diffraction patterns resulting from the application of a different filter at or near the output plane;
- inverse Fourier-transforming each of the diffraction patterns to produce an estimate of the corresponding wave at the output plane;
- and
- on the basis of the transformed diffraction patterns and the known characteristics of the filters, estimating the wave functions at the diffraction and specimen planes, including the amplitude and phase of previously unmeasured points.
2 more elements
Dependencies are inferred from the claim text.