# US 2012/0083882 A1 · Spinal implant structure and method for manufacturing the same

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- Number: US 2012/0083882 A1
- Document ID: US20120083882A1
- Status: Published application
- Kind: A1
- Application number: 12/977,363
- Filed: 2010-12-23
- Published: 2012-04-05
- Earliest claimed: 2010-10-01
- Assignees: Metal Industries Research & Development Centre
- Inventors: WEI- JEN SHIH; Yu-hsien Kao; Wei-Te Chen; Yen-Nien Chen; Jin-Long Jou
- Web page: https://patentgrep.com/patent/US20120083882A1

## CPC

- A61B 17/7059: {Cortical plates (A61B17/7007, A61B17/7058 take precedence)}
- A61B 17/8085: {with pliable or malleable elements or having a mesh-like structure, e.g. small strips (A61B17/8071, A61B17/8076 take precedence)}
- A61F 2/30942: {for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques}
- A61F 2/4405: {for apophyseal or facet joints, i.e. between adjacent spinous or transverse processes (devices implanted between spinous or transverse processes A61B17/7062)}
- A61F 2/4455: {for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages (intervertebral discs A61F2/442)}
- A61F 2002/30064: {Coating or prosthesis-covering structure made of biodegradable material}
- A61F 2002/30785: {parallel}
- A61F 2002/30787: {inclined obliquely with respect to each other}
- A61F 2002/30971: {Laminates, i.e. layered products}
- A61F 2310/00023: Titanium or titanium-based alloys, e.g. Ti-Ni alloys
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)

## Abstract

A spinal implant structure includes a hollow cylinder and a biodegradable polymer membrane. The hollow cylinder is implanted in a bone damaged part of human vertebra. The biodegradable polymer membrane is formed to a part of a surface of the hollow cylinder. Thus, the biodegradable polymer membrane blocks invasion of soft tissues, and then the bone fillers integrated with vertebra are maintained without loss.

## Claims

### Claim 1

A spinal implant structure, comprising:
a hollow cylinder, implanted in a bone damaged part of human vertebra, and having a sealed bottom; and
a biodegradable polymer membrane, formed on a part of a surface of the hollow cylinder.

### Claim 2 (depends on 1)

The spinal implant structure according to claim 1, wherein the hollow cylinder is fabricated by a moldable material.

### Claim 3 (depends on 2)

The spinal implant structure according to claim 2, wherein the moldable material of the hollow cylinder is pure titanium or titanium alloy.

### Claim 4 (depends on 1)

The spinal implant structure according to claim 1, wherein a wall thickness of the hollow cylinder is 20 μm to 200 μm.

### Claim 5 (depends on 1)

The spinal implant structure according to claim 1, wherein the hollow cylinder is a titanium mesh processed from a titanium foil with a geometric array of holes having a diameter of 1 mm to 4 mm.

### Claim 6 (depends on 5)

The spinal implant structure according to claim 5, wherein the hole is a diamond-shaped hole or a circular hole.

### Claim 7 (depends on 1)

The spinal implant structure according to claim 1, wherein the biodegradable polymer membrane is made of a chitosan, a collagen, or a gelatin.

### Claim 8

A method for manufacturing a spinal implant structure, comprising:
processing a array of holes in a moldable titanium foil, so as to form a titanium mesh;
processing and curling the titanium mesh into a hollow cylinder, and sealing an end of the hollow cylinder; and
forming a polymer membrane on a part of a surface of the hollow cylinder to.

### Claim 9 (depends on 8)

The method for manufacturing a spinal implant structure according to claim 8, wherein the titanium foil is made of pure titanium or titanium alloy.

### Claim 10 (depends on 8)

The method for manufacturing a spinal implant structure according to claim 8, wherein a diameter of the holes is 1 mm to 4 mm.

### Claim 11 (depends on 8)

The method for manufacturing a spinal implant structure according to claim 8, wherein the holes are diamond-shaped holes or circular holes.

### Claim 12 (depends on 8)

The method for manufacturing a spinal implant structure according to claim 8, further comprising immersing the titanium mesh in hydrochloric acid for surface roughness treatment.

### Claim 13 (depends on 8)

The method for manufacturing a spinal implant structure according to claim 8, wherein the hollow cylinder is abutted in a holding mold, and an aqueous solution of chitosan is injected to generate the polymer membrane.

### Claim 14 (depends on 13)

The method for manufacturing a spinal implant structure according to claim 13, further comprising placing the hollow cylinder contacting with the aqueous solution of chitosan in an oven for being dried; then, performing cross-linking in presence of sodium hydroxide at room temperature; and placing the hollow cylinder in the oven again for being dried, so as to generate the polymer membrane.