Medical device with degradation-retarding coating
AssigneeSofradim Production
InventorsSèbastien Ladet, Philippe Gravagna
Life of this patent
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Abstract
The present disclosure relates to implantable bioabsorbable medical devices having an amphiphilic coating for delaying the degradation of the device and methods of making such devices.
Claims11
A medical device comprising a bioabsorbable polymeric substrate having a coating, the coating comprising an amphiphilic compound having a hydrophilic portion and a hydrophobic portion, the hydrophobic portion of the amphiphilic compound being covalently bonded to the bioabsorbable polymeric substrate.
A method of increasing the degradation time of a bioabsorbable medical device, the method comprising:
- providing a coating on the medical device by reacting 1) a bioabsorbable polymeric substrate functionalized with a first reactive member with 2) an amphiphilic compound having a hydrophobic portion and a hydrophilic portion, the hydrophobic portion including a second, complementary reactive member.
A method of providing a medical device with an amphiphilic coating comprising functionalizing at least a portion of the medical device with a first reactive member and reacting the functionalized portion of the medical device with an amphiphilic compound having a hydrophobic portion and a hydrophilic portion, the hydrophobic portion including a second reactive member that is complementary to the first reactive member.
Dependencies are inferred from the claim text.