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US 2012/0071967 A1Published application
One-step phosphorylcholine-linked polymer coating and drug loading of stent
AssigneeAbbott Laboratories
InventorsPeter J. Tarcha, David Pecosky
Life of this patent
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Abstract
A one step method for drug coating an interventional device is disclosed by mixing a drug with a phosphorylcholine-linked methacrylate polymer in a liquid and applying the mixture to an interventional device, such as a stent, in a single step.
Claims32
A drug eluting interventional device produced by a method comprising:
- providing an interventional device having a bare surface;
- mixing at least one therapeutic agent and at least one polymer in a solvent to form a mixture;
- applying the mixture to at least a portion of the bare surface of the interventional device to form a coating thereon, wherein no base coating is applied to the surface of the interventional device;
- and
- crosslinking the at least one polymer by sterilizing the coated interventional device.
2 more elements
A drug eluting interventional device produced by a method comprising:
- providing an interventional device having an unactivated and bare surface;
- mixing at least one therapeutic agent and a phosphorylcholine polymer in a solvent to form a solution;
- applying the solution to at least a portion of the unactivated and bare surface of the interventional device to form a coating thereon, wherein no base coating is applied to the interventional device;
- and
- crosslinking the phosphorylcholine polymer by sterilizing the coated interventional device.
2 more elements
Dependencies are inferred from the claim text.