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US 2012/0071715 A1Published application
Material delivery system
AssigneeBy-Pass, Inc.
InventorsMordechay BEYAR, Oren Globerman, Rami Keller
Life of this patent
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Abstract
A method for injecting a therapeutic agent into a target tissue, the method comprising: (a) providing an expandable member; (b) positioning said expandable member in proximity to the target tissue; (c) Introducing the therapeutic agent into the expandable member until a desired pressure is achieved; and (d) creating a plurality of small apertures in the expandable member.
Claims38
A method for injecting a therapeutic agent into a target tissue, the method comprising:
- (a) providing an expandable member including an outer wall characterized by a plurality of exit sites therein, said outer wall defining an inner cavity;
- (b) filling the inner cavity with a flowing therapeutic agent to a defined pressure sufficient for performance of PTCA;
- (c) thereafter, increasing said pressure to a second pressure in excess of said defined pressure to open said exit sites;
- and
- (d) releasing the therapeutic agent through the exit sites, said second pressure being such that one or more jets are formed when the therapeutic agent is released through said open exit sites,
- (e) wherein the velocity of the released therapeutic agent is sufficient for the therapeutic agent to penetrate the target tissue.
3 more elements
A method for injecting a fluid to penetrate into a tissue, the method comprising:
- (a) expanding a member including an outer wall defining an inner cavity, and characterized by a plurality of exit sites therein;
- (b) filling said inner cavity with a flowing therapeutic agent at a desired pressure sufficient for performance of PTCA without significant leakage through said exit sites;
- and
- (c) releasing said therapeutic agent by transforming said exit sites into ejection ports through which the therapeutic agent can exit by increasing the pressure above said desired pressure at said exit sites;
- (d) and delivering said therapeutic agent through said ejection ports at a velocity sufficient to penetrate adjacent tissue, wherein said therapeutic agent is delivered into said target tissue in such a manner that it exerts a physiologic effect on cells of said target tissue but does not exert a substantial effect on cells lying at a distance greater than a selected distance from said target tissue.
2 more elements
Dependencies are inferred from the claim text.