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US 2012/0071705 A1Published application
Brachytherapy device for asymmetrical irradiation of a body cavity
AssigneeSenoRx, Inc.
InventorsPaul Lubock, Michael L. Jones, Frank R. Louw
Life of this patent
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Abstract
The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.
Claims21
A brachytherapy device for treating tissue surrounding a body cavity of a patient, comprising:
- a) a shaft having a proximal end, a distal end, a distal treatment portion proximal the distal end, and a longitudinal axis, the shaft having a plurality of off-set radiation delivery lumens radially off-set from the longitudinal axis that extend into the distal treatment portion, each of the plurality of off-set radiation delivery lumens being configured to receive a radiation source to asymmetrically irradiate tissue surrounding the body cavity at the distal treatment portion;
- and
- b) an expandable member coupled to the shaft to define an expandable volume that surrounds the distal treatment portion, the expandable member being configured to increase space between the expandable member and the the distal treatment portion as the expandable member is expanded.
2-6. (canceled)
A brachytherapy device for asymmetrical irradiation of a body cavity, comprising:
- an elongated shaft having a proximal end, a distal end, and a distal shaft portion proximal to the distal end, the elongated shaft having a centrally located longitudinal axis;
- and
- an expandable member coupled to the elongated shaft, the expandable member configured to have a deflated condition and an inflated condition to define an expandable volume at the distal shaft portion,
- the elongated shaft including:
- a plurality of off-set radiation delivery lumens radially off-set from the longitudinal axis having a substantially linear treatment portion positioned within the expandable volume defined by the expandable member, the plurality of off-set radiation delivery lumens being configured to extend longitudinally at least from the proximal end of the elongated shaft and into the distal shaft portion, with each radiation delivery lumen of the plurality of off-set radiation delivery lumens being configured to selectively receive a radiation source and guide the radiation source into the treatment portion, and
- an inflation lumen configured to extend longitudinally at least from the proximal end of the shaft, the inflation lumen being coupled in fluid communication with the expandable volume defined by the expandable member, and configured for connection to an inflation fluid source.
3 more elements
A brachytherapy device for asymmetrical irradiation of a body cavity, comprising:
- a flexible elongated shaft having a proximal end, a distal end, and a distal shaft portion proximal to the distal end;
- and
- an expandable member coupled to the elongated, the expandable member configured to have a deflated condition and an inflated condition to define an expandable volume at the distal shaft portion,
- the elongated shaft including:
- a central radiation delivery lumen and a plurality of off-set radiation delivery lumens radially off-set from the central radiation delivery lumen having a treatment portion positioned within the expandable volume defined by the expandable member, the treatment portion being configured to be spaced apart from the expandable member as the expandable member is expanded to the inflated condition, each off-set radiation delivery lumen of the plurality of off-set radiation delivery lumens and the central radiation delivery lumen being configured to extend longitudinally at least from the proximal end of the elongated shaft and into the distal shaft portion, with each radiation delivery lumen being configured to selectively receive at least one radiation source and guide the at least one radiation source into the treatment portion, and
- an inflation lumen configured to extend longitudinally at least from the proximal end of the shaft, the inflation lumen being coupled in fluid communication with the expandable volume defined by the expandable member, the inflation lumen being configured for connection to an inflation fluid source.
3 more elements
Dependencies are inferred from the claim text.