Beta-amino acids and methods and intermediates for making same
AssigneeNDSU Research Foundation
InventorsMukund P. SIBI, Craig P. Jasperse, Prabagaran Narayanasamy, Sandeep R. Ghorpade
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AssigneeNDSU Research Foundation
InventorsMukund P. SIBI, Craig P. Jasperse, Prabagaran Narayanasamy, Sandeep R. Ghorpade
Estimating the term…
Disclosed are β-amino acids that are unsubstituted in the β position; that are substituted in the β position with an aryl group; that are substituted in the α position with an aryl group; that bear two substituents in the α position; and/or that are substituted in the α and β positions with groups which, together with the carbon atoms at the α and β positions, form a ring. Also disclosed are methods for making the above-mentioned β-amino acids and other β-amino acids which involve providing an α,β-unsaturated imide; converting the α,β-unsaturated imide to a 2-substituted-isoxazolidin-5-one; and converting the 2-substituted-isoxazolidin-5-one to a β-amino acid.
A β-amino acid that is unsubstituted in the β position;
A method for making a β-amino acid comprising:
A method for making a β-amino acid comprising:
A 2-substituted-isoxazolidin-5-one that is unsubstituted in the 3 position;
An α,β-unsaturated imide that is substituted in the α position.
Dependencies are inferred from the claim text.