Anti-fungal formulation
AssigneeTopica Pharmaceuticals, Inc.
InventorsCharles G. VONTZ, Norifumi Nakamura, Catherine de Porceri-Morton, Jeff Hughes, Bhavesh Shah, Peter Gertas, Vitthal Kulkarni
Life of this patent
Estimating the term…
Abstract
Provided herein are compositions and formulations comprising an antifungal agent. Pharmaceutical compositions comprising luliconazole in an amount effective for the treatment of onychomycosis are provided. Also provided are methods for treating dermatomycoses and onychomycosis using the compositions and formulations.
Claims24
A pharmaceutical composition, comprising:
- from 5 weight percent to 15 weight percent luliconazole;
- from 5 weight percent to 25 weight percent acetone;
- from 1 weight percent to 15 weight percent propylene carbonate;
- from 15 weight percent to 35 weight percent of an ethylene glycol derivative of the formula HOCH2CH2OCH2CH2OR where R is an alkyl group having 1 to 6 carbon atoms;
- and
- from 0.01 weight percent to 6 weight percent benzyl alcohol.
A method of treating onychomycosis in an individual in need thereof, comprising contacting the individual's nail with a pharmaceutical composition comprising:
- from 5 weight percent to 15 weight percent luliconazole;
- from 5 weight percent to 25 weight percent acetone;
- from 1 weight percent to 15 weight percent propylene carbonate;
- from 15 weight percent to 35 weight percent of an ethylene glycol derivative of the formula HOCH2CH2OCH2CH2OR where R is an alkyl group having 1 to 6 carbon atoms;
- and
- from 0.01 weight percent to 6 weight percent benzyl alcohol.
Dependencies are inferred from the claim text.