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US 2012/0071532 A1Published application
Novel solid forms of bendamustine hydrochloride
AssigneeCephalon, Inc.
InventorsMartin Ian Cooper, Laurent D. Courvoisier, Mark Eddleston, Robert E. McKean
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Abstract
Novel solid forms of bendamustine hydrochloride are described, as well as methods of their preparation and use.
Claims40
A solid form of bendamustine hydrochloride that comprises at least one of bendamustine hydrochloride Form 1, bendamustine hydrochloride Form 3, bendamustine hydrochloride Form 4, amorphous bendamustine hydrochloride, or a mixture thereof.
A method for preparing a lyophilized composition that comprises at least one crystalline form of bendamustine hydrochloride, said method comprising the steps of:
- combining bendamustine hydrochloride with at least one solvent to form a solution;
- and lyophilizing the solution.
Dependencies are inferred from the claim text.