Fentanyl-containing adhesive preparation for external use
AssigneeTeikoku Seiyaku Co., Ltd.
InventorsMamoru Naruse, Kenichi Hattori, Kunihiko Matsushita
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Abstract
Disclosed is a fentanyl-containing adhesive preparation for external use, wherein an adhesive layer is laminated on a supporting body. The adhesive layer contains SIS, a tackifier resin that is composed of a rosin resin and terpene resin, and a softener that is composed of a plybutene and a liquid paraffin. The adhesive layer also contains fentanyl as an active ingredient. The fentanyl-containing adhesive preparation for external use has excellent skin permeation of fentanyl and high preparation stability, without suffering from crystallization of fentanyl during storage.
Claims3
A fentanyl-containing patch for external use prepared by adding fentanyl as an active ingredient to the adhesive layer containing
- 5 to 50% by weight per total amount of the adhesive layer of a styrene-isoprene-styrene block copolymer,
- 30 to 60% by weight per total amount of the adhesive layer of a tackifier resin consisting of a rosin resin and a terpene resin
- and 5 to 40% by weight per total amount of the adhesive layer of a softener consisting of polybutene and liquid paraffin.
Dependencies are inferred from the claim text.