Melting tablet containing a sildenafil salt
Assigneeratiopharm GmbH
InventorsSven Winter, Max-Werner Scheiwe
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Abstract
The invention relates to an orodispersible tablet comprising the components pharmaceutically acceptable sildenafil salt (a), polymeric adsorbent (b), in particular cation exchanger resin, sweetener (c), and flavoring (d) and, preferably, mucilage (e) and glidant (f). The invention furthermore relates to a process for the preparation of orodispersible tablets comprising a pharmaceutically acceptable sildenafil salt and to the use of a combination of cation exchanger resin and mucilage for masking the flavor of medicaments for treating erectile dysfunction
Claims18
An orodispersible tablet comprising:
- (a) a pharmaceutically acceptable sildenafil salt;
- (b) a polymeric adsorbent;
- (c) a sweetener;
- and
- (d) a flavoring component.
A process for the preparation of an orodispersible tablet comprising a pharmaceutically acceptable salt of sildenafil, the process comprising the steps of:
- (i) mixing a pharmaceutically acceptable sildenafil salt with pharmaceutical adjuvants, and
- (ii) compressing the mixture, the process being carried out in the absence of solvents.
The use of a combination of cation exchanger resin and mucilage for masking the flavor of medicaments for treating erectile dysfunction, in particular for masking the flavor of sildenafil citrate.
Dependencies are inferred from the claim text.