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US 2012/0071487 A1Published application
Piperazine, piperidine and tetrahydropyridine derivatives and their pharmaceutical use
AssigneeATIR Holding S.A.
InventorsVladimir Kogan, Lev Tabachnik
Life of this patent
Estimating the term…
Abstract
Novel piperazine, piperidine and tetrahydropyridine derivatives comprising a dibenzofurane moiety are provided herein, as well as pharmaceutical compositions comprising same and therapeutic uses thereof.
Claims18
1-23. (canceled)
A compound of formula Id or Ie:
- wherein:
- R1, R2 and R3 are independently selected from the group consisting of C1-C5 alkyl, —OH, —SH, halogen, alkoxy, NO2, and —CN;
- m is 0, 1, 2, 3, 4 or 5;
- n is 0, 1, 2 or 3;
- and
- p is 0, 1, 2, 3 or 4.
3 more elements
A compound of formula I(a):
- wherein:
- R2 and R3 are independently selected from the group consisting of C1-C5 alkyl, —OH, —SH, halogen, alkoxy, NO2, and —CN;
- m is 0, 1, 2 or 3, and when m is other than 0, then R1 is hydroxy;
- n is 0, 1, 2 or 3;
- and
- p is 0, 1, 2, 3 or 4.
3 more elements
A compound of formula I:
- wherein:
- Y1 and Y2 are independently CH, C(R1) or N;
- X is N, CH or C, with the proviso that when X is C, then the broken line represents a chemical bond;
- R1, R2 and R3 are independently selected from the group consisting of C1-C5 alkyl, —OH, —SH, halogen, alkoxy, NO2, and —CN;
- m is 0, 1, 2, 3, 4 or 5;
- n is 0, 1, 2 or 3;
- and
- p is 0, 1, 2, 3 or 4.
5 more elements
Dependencies are inferred from the claim text.