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US 2012/0071462 A1Published application
Dihydrobenzoxathiazepine compounds, a process for their preparation and pharmaceutical compositions containing them
AssigneeLes Laboratoires Servier
InventorsAlexis Cordi, Patrice Desos, Pierre Lestage, Laurence Danober
Life of this patent
Estimating the term…
Abstract
Compounds of formula (I): wherein R1 represents a hydrogen atom or a heterocyclic, cyano, alkoxycarbonyl, alkylsulphonylaminoalkyl or N-hydroxycarboximidamide group. Medicinal products containing the same which are useful as modulators of the AMPA receptor.
Claims13
A compound selected from those of formula (I):
- wherein R1 represents a hydrogen atom, a cyano group, a linear or branched (C1-C6)alkoxycarbonyl group, a (C1-C6)alkylsulphonylamino-(C1-C6)alkyl group in which the alkyl moieties may each be linear or branched, an N-hydroxycarboximidamide group or a heterocyclic group,
- its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base,
- wherein the term “heterocyclic group” means a 5-membered monocyclic aromatic group having one to four hetero atoms which may be the same or different and which are selected from nitrogen, oxygen and sulphur, wherein the heterocyclic group may be optionally substituted by one or more substituents selected from linear or branched (C1-C6)alkyl and linear or branched (C1-C6)polyhaloalkyl.
A compound selected from those of formula (V):
- wherein Hal represents a halogen atom such as fluorine, chlorine or bromine.
Dependencies are inferred from the claim text.