DNA Virus MicroRNA and Methods for Inhibiting Same
AssigneeThe Rockefeller University
InventorsSebastien Pfeffer, Thomas Tuschl
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Abstract
The invention relates to isolated nucleic acid molecules comprising the sequence of a human cytomegalovirus microRNA. In another embodiment, the invention relates to single stranded DNA virus microRNA molecules comprising the sequence of a human cytomegalovirus microRNA. The invention also relates to the anti-DNA virus microRNA molecules.
Claims42
An isolated nucleic acid Epstein Barr virus (EBV) microRNA molecule having a maximum of 50 nucleotides comprising any one of SEQ ID NOS:
- 1 and 3-5.
An isolated nucleic acid EBV hairpin precursor microRNA molecule having a maximum of 300 nucleotides comprising any one of SEQ ID NOS:
- 6-10.
An isolated single stranded nucleic acid EBV anti-microRNA molecule having a maximum of 50 moieties, each moiety comprising a base bonded to a backbone unit, said molecule comprising any one of SEQ ID NOS:
- 11-15.
Dependencies are inferred from the claim text.