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US 2012/0070846 A1Published application
Methods for detecting molecule-molecule interactions with a single detection channel
AssigneesThe Texas A&M University System, Board of Regents, The University of Texas System
InventorsJun Kameoka, Nan Jing, Mien-chie Hung, Chao-Kai Chou
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Abstract
A single molecule or molecule complex detection method is disclosed in certain aspects, comprising nano- or micro-fluidic channels.
Claims14
A method comprising:
- (a) contacting a sample with a binding moiety that specifically binds to a target molecule of the sample;
- (b) contacting the binding moiety with a detection moiety forming a detection complex;
- (c) introducing the sample containing the detection complex into a channel of at least 100 nm in width;
- and
- (d) detecting the complex by 2D photon counting.
2 more elements
Dependencies are inferred from the claim text.