Novel Compounds and Derivatizations of DNAs and RNAs on the Nucleobases of Pyrimidines for Function, Structure and Therapeutics
AssigneeSeNA Research, Inc.
InventorZhen Huang
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Abstract
Disclosed are compounds of formula (I), a derivative, or a tautomer thereof, or a pharmaceutically acceptable salt of said compound or said tautomer. Also disclosed are methods of preparing compound of formula (I), a derivative, or a tautomer thereof, or a pharmaceutically acceptable salt of said compound or said tautomer. Further disclosed are methods of conducting drug discovery and research comprises applying the compound of formula (I), a derivative, or a tautomer thereof, or a pharmaceutically acceptable salt of said compound or said tautomer in an investigation.
Claims21
A compound of formula (I), or a tautomer thereof, or a derivative thereof, or a pharmaceutically acceptable salt of said compound or said tautomer or said derivative;
- wherein:
- R1 is selected from the group consisting of is hydroxyl, thiol, alkylthiol, arylthiol, selenol, alkylseleno, arylseleno, tellurol, alkyltelluro, aryltelluro, amino, alkylamino, arylamino and acylamino;
- R2 is selected from the group consisting of oxygen, sulfur, selenium, tellurium, amino, alkylamino, arylamino and acylamino;
- R3 is a hydrogen or a hydroxyl group;
- X1 is selected from the group consisting of oxygen, sulfur, selenium, tellurium, amino, alkylamino, arylamino, acylamino, carbon and hydrogen;
- X2 is linear or branched alkyl, or aryl;
- X3 is selected from the group consisting of hydrogen, halogen, alkyl, aryl, hydroxyl, thiol, amino, alkyloxyl, aryloxyl, acyloxyl, alkylthiol, arylthiol, alkylseleno, arylseleno, alkyltelluro, aryltelluro, alkylamino, arylamino and acylamino;
- and
- N is a subscript selected from 0 to 20.
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Dependencies are inferred from the claim text.