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AssigneeKorea Institute of Science and Technology
InventorsDong Keun Han, Kwi Deok Park, Jong Hee Kang, Bong Soo Lee, Ji Yeon Choi, Chang Hun Kum
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Disclosed are biomedical implants comprising surface-modified metal particles and biodegradable polymers; its use for suppressing inflammation; and a method for preparing a biomedical material, comprising: (a) modifying surface of basic metal particles with a polymer to obtain surface-modified metal particles; and (b) mixing the surface-modified metal particles with a biodegradable polymer, followed by manufacturing a biodegradable biomedical implant, or coating the resulting mixture on a conventional biomedical implant.
A biomedical implant, comprising:
A method for preparing a biomedical implant comprising basic metal particles of which surface are modified with a polymer and a biodegradable polymer, comprising:
A method for removing acidic byproducts generated from the degradation of a biomedical implant using an acid-base neutralization reaction by making the biomedical implant containing surface-modified basic metal particles in an amount of 1 to 99 wt % with respect to total weight of the biomedical implant.
A method for improving physical and mechanical properties of a biomedical implant made of a biodegradable polymer, or a layer of a biodegradable polymer coated on a biomedical implant, by making the biomedical implant contained surface-modified basic metal particles in an amount of 1 to 99 wt % with respect to total weight of the biomedical implant, so as to prevent an interface separation between a metal and biodegradable polymers.
Dependencies are inferred from the claim text.