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AssigneeNatrogen Therapeutics International, Inc.
InventorsLonggui Wang, Xiao Mei Liu, Simon K. Mencher, James P. McCarron, JR.
Estimating the term…
The present invention is directed to topical compositions and methods for topically treating psoriasis comprising meisoindigo as an active ingredient. The topical compositions preferably further comprise skin penetration enhancers, pharmaceutical surfactants and solubility enhancers, oil phase components, aqueous phase components, emulsifiers, moisturizers, antioxidants, vitamins, lubricants, herbal extracts, preservatives, and other ingredients. In addition to meisoindigo, the compositions may comprise other agents commonly used to topically treat psoriasis. The disclosed methods have been demonstrated to effectually treat moderate and severe forms of psoriasis to a degree similar to a potent corticosteroid without side effects. Preferably, the method involves topical application of the disclosed compositions to affected epidermal areas twice a day. In addition, the disclosed methods may be used in conjunction with other common therapies in the treatment of psoriasis.
A method of treating a psoriasis, the method comprising the step of topically applying a composition comprising meisoindigo in a pharmaceutically acceptable carrier to the affected epidermal area on a subject in need.
A topical composition for treating psoriasis comprising a therapeutically effective amount of meisoindigo and a pharmaceutically acceptable topical carrier.
The topical composition of claim 21, wherein the solubility enhancer is ethyl acetate.
A topical composition comprising the following ingredients by weight:
Dependencies are inferred from the claim text.