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AssigneesSumalogic, Inc., Sumitomo Bakelite Co., Ltd.
InventorsMitsutaka MATSUMOTO, Sumio SHIBAHARA, Takayuki MATSUMOTO, Kanehisa YOKOYAMA, Sohei FUNAOKA, Daisuke MASUDA, Michael Patrick COLEMAN, Dominic ZICHI
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A biochip substrate capable of realizing the high detection accuracy by restricting a nonspecific adsorption or bonding of a substance to be detected, when used for a detection or analysis of protein, nucleic acids and the like. The biochip substrate is for fixing a biologically active substance on a surface of a solid substrate, and characterized in that it has a layer comprising a polymer compound obtained by copolymerizing an ethylenically unsaturated polymerizable monomer having an alkylene glycol residue, an ethylenically unsaturated polymerizable monomer having a functional group for fixing a biologically active substance and an ethylenically unsaturated polymerizable monomer having a cross-linkable functional group, on the surface of the substrate.
A polymer compound for biomedical use obtained by copolymerizing an ethylenically unsaturated polymerizable monomer (a) having an alkylene glycol residue, an ethylenically unsaturated polymerizable monomer (b) having a functional group for fixing a biologically active substance and an ethylenically unsaturated polymerizable monomer (c) having a cross-linkable functional group.
A surface coating material for biomedical use comprising a polymer compound for biomedical use obtained by copolymerizing an ethylenically unsaturated polymerizable monomer (a) having an alkylene glycol residue, an ethylenically unsaturated polymerizable monomer (b) having a functional group for fixing a biologically active substance and an ethylenically unsaturated polymerizable monomer (c) having a cross-linkable functional group.
A biochip substrate obtained by forming a layer comprising a polymer compound for biomedical use on a surface of a supporting substrate, the polymer compound for biomedical used obtained by copolymerizing an ethylenically unsaturated polymerizable monomer (a) having an alkylene glycol residue, an ethylenically unsaturated polymerizable monomer (b) having a functional group for fixing a biologically active substance and an ethylenically unsaturated polymerizable monomer (c) having a cross-linkable functional group, the supporting substrate made of a saturated cyclic polyolefin.
A method of manufacturing a biochip substrate, the method comprising the processes of:
A biochip obtained by fixing a biologically active substance on a layer comprising a polymer compound for biomedical use of a biochip substrate obtained by forming a layer comprising a polymer compound for biomedical use on a surface of a supporting substrate, the polymer compound for biomedical use obtained by copolymerizing an ethylenically unsaturated polymerizable monomer (a) having an alkylene glycol residue, an ethylenically unsaturated polymerizable monomer (b) having a functional group for fixing a biologically active substance and an ethylenically unsaturated polymerizable monomer (c) having a cross-linkable functional group.
Dependencies are inferred from the claim text.