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US 2012/0070456 A1Published application
Polypeptide carrier protein
OwnerRino Rappuoli, Guido Grandiinventors
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Abstract
The invention relates to polypeptide carrier proteins that comprise at least five CD4+ T cell epitopes, for conjugation to capsular polysaccharides. The carrier proteins are useful as components of vaccines that can elicit a T-cell dependent immune response. These vaccines are particularly useful to confer protection against infection from encapsulated bacteria in infants between the ages of 3 months and about 2 years.
Claims31
A carrier protein comprising at least five CD4+ T cell epitopes.
A carrier protein which comprises one or more of N6, N10 or N19 proteins.
Dependencies are inferred from the claim text.