Immunoadjuvant composition and use thereof
AssigneeOsaka University
InventorsShizuo Akira, Osamu Takeuchi, Kazufumi Matsushita, Ken Ishii
Life of this patent
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Abstract
Disclosed is a composition comprising, as an active ingredient, at least one selected from the group consisting of a Zc3h12a gene inhibitor and a Zc3h12a protein inhibitor. This composition can be used as an immunoadjuvant.
Claims12
An immunoadjuvant composition comprising, as an active ingredient, at least one selected from the group consisting of a Zc3h12a gene inhibitor and a Zc3h12a protein inhibitor.
A vaccine composition comprising a vaccine antigen and at least one selected from the group consisting of a Zc3h12a gene inhibitor and a Zc3h12a protein inhibitor.
A production process for an activated immune cell, comprising the step of bringing an immune cell harvested from a subject into contact with at least one selected from the group consisting of a Zc3h12a gene inhibitor and a Zc3h12a protein inhibitor, thereby activating the immune cell.
A compound for enhancing the immunogenicity of a vaccine antigen, the compound being at least one selected from the group consisting of a Zc3h12a gene inhibitor and a Zc3h12a protein inhibitor.
A use of a compound for producing an immunoadjuvant, the compound being at least one selected from the group consisting of a Zc3h12a gene inhibitor and a Zc3h12a protein inhibitor.
A process for enhancing the immunogenicity of a vaccine antigen, comprising the step of mixing the vaccine antigen with at least one selected from the group consisting of a Zc3h12a gene inhibitor and a Zc3h12a protein inhibitor.
A composition for activating immunity, the composition comprising a vaccine antigen and at least one selected from the group consisting of a Zc3h12a gene inhibitor and a Zc3h12a protein inhibitor.
A use of a composition comprising a vaccine antigen and at least one selected from the group consisting of a Zc3h12a gene inhibitor and a Zc3h12a protein inhibitor, for producing a vaccine composition.
Dependencies are inferred from the claim text.