Anti-il-3ra antibody for use in treatment of blood tumor
AssigneeKyowa Hakko Kirin Co., Ltd.
InventorsTomonori Tawara, Shinichiro Takayanagi, Yoshimasa Inagaki
Life of this patent
Estimating the term…
Abstract
The present invention provides an antibody to human IL-3Rα chain, which does not inhibit IL-3 signaling and binds to B domain of the human IL-3Rα chain but does not bind to C domain of the human IL-3Rα chain; a composition for preventing or treating a blood tumor in which a cell expressing IL-3Rα is found in bone marrow or peripheral blood of a subject, which comprises the antibody to human IL-3Rα as an active ingredient; and a method for treating a blood tumor in which a cell expressing IL-3Rα is found in bone marrow or peripheral blood, which comprises administering, to a subject, a composition comprising the IL-3Rα antibody as an active ingredient.
Claims9
An antibody to a human IL-3Rα chain, which does not inhibit IL-3 signaling and binds to B domain of the human IL-3Rα chain but does not bind to C domain of the human IL-3Rα chain.
Dependencies are inferred from the claim text.