Extracellular yaluronidase from streptomyces koganeiensis
AssigneeKeter Plastic Ltd.
InventorsLuciano Messina, Susana Vaccaro, Salvatore Caruso, Giovanni Gennari
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Abstract
The invention relates to Streptomyces koganeiensis ATCC 31394 hyaluronidase having molecular weight of 21.6 kDalton, which has hyaluronidase activity and stability markedly higher than those of the hyaluronidase obtained from such microorganism to date. The invention further relates to a process for the isolation and purification of said hyaluronidase and its use for the preparation of pharmaceutical compositions or as an analytical reagent.
Claims15
Hyaluronidase from Streptomyces koganeiensis ATCC 31394 comprising the N-terminal amino acid sequence shown in SEQ ID No. 1.
-7. (canceled)
Dependencies are inferred from the claim text.