Contact Lens Care System with Peroxide
AssigneeBausch & Lomb Incorporated
InventorKimberly A. Millard
Life of this patent
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Abstract
A contact lens disinfection system that includes a peroxide disinfection solution in combination with a lens closure. The disinfection solution comprises 0.5 wt. % to 6 wt. % hydrogen peroxide or a chemical precursor of hydrogen peroxide, and an amino buffer component. The closure includes securing elements to position and maintain a pair of contact lenses in the disinfection solution, and a peroxide neutralization catalyst comprising platinum. In combination with the closure, the disinfection solution exhibits a pseudo first-order, half-life of hydrogen peroxide over an initial sixty minutes of neutralization from 12 minutes to 30 minutes in the lens closure.
Claims18
A contact lens disinfection system comprising:
- a peroxide disinfection solution comprising 0.5 wt. % to 6 wt. % hydrogen peroxide or a chemical precursor of hydrogen peroxide, and an amino buffer component;
- in combination with a lens closure comprising securing elements to position and maintain a pair of contact lenses in the disinfection solution, and a peroxide neutralization catalyst comprising platinum,
- wherein the disinfection system exhibits a pseudo first-order, half-life of hydrogen peroxide over an initial sixty minutes of neutralization from 12 minutes to 30 minutes in the lens closure.
A contact lens disinfection system comprising:
- a peroxide disinfection solution comprising 0.5 wt. % to 6 wt. % hydrogen peroxide or a chemical precursor of hydrogen peroxide, and an amino buffer component;
- in combination with a lens closure comprising securing elements to position and maintain a pair of contact lenses in the disinfection solution, and a peroxide neutralization catalyst comprising platinum;
- wherein the disinfection system exhibits greater biocidal efficacy against Candida albicans or Serratia marcescens by 0.5 log-kill or greater after six hours than an equivalent contact lens disinfection solution in the absence of the amino buffer component, the increase in effectivness against Candida albicans or Serratia marcescens is provided by a delay in peroxide neutralization of the solution.
A contact lens disinfection system comprising:
- a peroxide disinfection solution comprising 0.5 wt. % to 6 wt. % hydrogen peroxide or a chemical precursor of hydrogen peroxide, and an amino buffer component selected from the group consisting of 2-amino-2-hydroxymethyl-1,3-propane diol, 2-[Bis(2-hydroxyethypamino]-2-(hydroxymethyl)-1,3-propanediol and N-(2-acetoamido)-2-aminoethanesulfonic acid;
- in combination with a lens closure comprising securing elements to position and maintain a pair of contact lenses in the disinfection solution, and a peroxide neutralization catalyst comprising platinum,
- wherein the disinfection system exhibits a pseudo first-order, half-life of hydrogen peroxide over an initial sixty minutes of neutralization from 12 minutes to 30 minutes in the lens closure.
Dependencies are inferred from the claim text.