Method of correcting for oxygen effect on test sensors
AssigneeBayer HealthCare LLC
InventorJing Lin
Life of this patent
Estimating the term…
Abstract
An electrochemical test sensor is adapted to measure glucose and correct for the oxygen effect in a fluid sample. The test sensor comprises a base, first and second working electrodes, and a counter electrode. The first working electrode includes glucose oxidase, a mediator and peroxidase. The second working electrode includes glucose oxidase and the mediator. The first working electrode, the second working electrode and the counter electrode are located on the base. In other embodiments, an electrochemical test sensor is adapted to measure cholesterol, lactate, pyruvate or xanthine and correct for the oxygen effect in a fluid sample.
Claims22
-15. (canceled)
A method for correcting the oxygen effect in determining the concentration of glucose using an electrochemical test sensor, the method comprising the acts of:
- providing a test sensor, the test sensor comprising a base, first and second working electrodes, and a counter electrode, the first working electrode including glucose oxidase, a mediator and peroxidase, the second working electrode including glucose oxidase and the mediator, the first working electrode, the second working electrode and the counter electrode being adjacent to the base;
- contacting the test sensor to a meter to form an electrical connection;
- placing a fluid on the test sensor;
- measuring a first current from the first working electrode;
- measuring a second current from the second working electrode;
- and
- determining the concentration of glucose and correcting for the oxygen effect by using the first current measurement and the second current measurement.
-72. (canceled)
A method for correcting the oxygen effect in determining the concentration of glucose using an electrochemical test sensor, the method comprising the acts of:
- providing a test sensor, the test sensor comprising a base, first and second working electrodes, and a counter electrode, the first working electrode including glucose oxidase, a mediator and peroxidase, the second working electrode including glucose oxidase and the mediator in the absence of the peroxidase, the first working electrode, the second working electrode and the counter electrode being adjacent to the base;
- contacting the test sensor to a meter to form an electrical connection;
- placing a fluid on the test sensor;
- measuring a first current from the first working electrode;
- measuring a second current from the second working electrode;
- and
- determining the concentration of glucose and correcting for the oxygen effect by using the first current measurement and the second current measurement.
A method for correcting the oxygen effect in determining the concentration of cholesterol using an electrochemical test sensor, the method comprising the acts of:
- providing a test sensor, the test sensor comprising a base, first and second working electrodes, and a counter electrode, the first working electrode including cholesterol oxidase, a mediator and peroxidase, the second working electrode including cholesterol oxidase and the mediator, the first working electrode, the second working electrode and the counter electrode being adjacent to the base;
- contacting the test sensor to a meter to form an electrical connection;
- placing a fluid on the test sensor;
- measuring a first current from the first working electrode;
- measuring a second current from the second working electrode;
- and
- determining the concentration of cholesterol and correcting of the oxygen effect using the first current measurement and the second current measurement.
A method for correcting the oxygen effect in determining the concentration of at least one of lactate, pyruvate or xanthine using an electrochemical test sensor, the method comprising the acts of:
- providing a test sensor, the test sensor comprising a base, first and second working electrodes, and a counter electrode, the first working electrode including lactate, pyruvate or xanthine oxidase, a mediator and peroxidase, the second working electrode including lactate, pyruvate or xanthine oxidase and the mediator, the first working electrode, the second working electrode and the counter electrode being adjacent to the base;
- contacting the test sensor to a meter to form an electrical connection;
- placing a fluid on the test sensor;
- measuring a first current from the first working electrode;
- measuring a second current from the second working electrode;
- and
- determining the concentration of lactate, pyruvate or xanthine and correcting of the oxygen effect using the first current measurement and the second current measurement.
Dependencies are inferred from the claim text.