Endovascular Electrostimulation Near a Carotid Bifurcation in Treating Cerebrovascular Conditions
AssigneeSamson Neurosciences Ltd.
InventorAlon Shalev
Life of this patent
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Abstract
An interventional system that utilizes a carotid chemoreceptor(s) and optionally baroreceptor(s) for inducing vasodilatation in blood vessels of the brain is provided for treating ischemic conditions of the CNS, such as ischemic stroke and cerebral vasospasm. The system includes an electrical signal generator and an endovascular module with electrode units for transiently being disposed in the internal and external carotid arteries, adjacent a carotid body.
Claims16
1-14. (canceled)
A system for treating a cerebrovascular condition in a living body comprising:
- i) an implantable elongated electrostimulation module comprising a proximal end and a distal end, said distal end comprising a branching point at which said distal end is branched into at least a first and a second distal end member;
- (ii) At least one metallic electrode mounted to each of said first and second distal end members;
- (iii) An electromagnetic transceiver disposed at said proximal end;
- (iv) at least one conductive galvanically distinct wire extending through said module and connecting said transceiver with each of said electrodes;
- and (v) An electrical signal generator for producing an electrical waveform to be coupled to said electrodes;
- said module being sized and shaped for transient endovascular positioning near a carotid body of said living body, said branching point being adjacent to the bifurcation of said carotid, said at least first and second distal end members being inserted to internal and external carotid arteries, thereby enabling the stimulation by said electrodes of chemoreceptors and optionally baroreceptors in said arteries adjacent to said bifurcation.
A system for treating a cerebrovascular condition in a living body comprising:
- i) an implantable elongated electrostimulation module comprising a proximal end and a distal end, said distal end comprising at least one selected from (a) at least one first distal end member;
- (b) at least one second distal end member;
- or, (c) at least one first distal end member and at least one second distal end member ;
- (ii) At least one metallic electrode mounted to a least one selected from (a) said at least one first distal end member and;
- (b) said at least one second distal end member;
- or, (c) said at least one first distal end member and said at least one second distal end member:
- (iii) An electromagnetic transceiver disposed at said proximal end;
- (iv) at least one conductive galvanically distinct wire extending through said module and connecting said transceiver with each of said electrodes;
- and (v) an electrical signal generator for producing an electrical waveform to be coupled to said electrodes;
- said module being sized and shaped for transient endovascular positioning near a carotid body of said living body, said distal end being adjacent to the bifurcation of said carotid, said at least first and second distal end members being inserted to either the (a) internal carotid artery;
- (b) the external carotid artery;
- (c) internal and the external carotid arteries, thereby enabling the stimulation by said electrodes of chemoreceptors and optionally baroreceptors in said arteries adjacent to said bifurcation.
Dependencies are inferred from the claim text.