Implantable Micro-Generator Devices with Optimized Configuration, Methods of Use, Systems and Kits Therefor

An implantable cardiac rhythm management system comprising:

• a cardiac rhythm management device;
• an elongated housing adapted and configured to be positioned distally within a tip of a cardiac lead wherein the housing has an elongated interior cavity, a first end and a second end;
• one or more longitudinally slidable elongated magnets;
• one or more coils positioned exteriorly, interiorly or integrally along at least a portion of the housing;
• a power wire in electrical communication with the one or more coils and with an implantable medical device;
• wherein the implantable cardiac rhythm management system is adapted and configured to generate energy and communicate the generated energy to the implantable medical device.

An implantable tissue stimulation device comprising:

• a power supply;
• an electrode;
• a tissue stimulator connected to the power supply, the tissue stimulator being adapted to generate a tissue stimulation signal for delivery to the tissue stimulation target through the electrode;
• a controller connected to the power supply, and further connected to the neural stimulator to control the neural stimulator according to a tissue stimulation protocol to deliver a tissue stimulation therapy;
• a pressure sensor electrically connected to the controller;
• and
• an implantable micro-generator comprising, an elongated housing adapted and configured to be positioned distally within a tip of a cardiac lead wherein the housing has an elongated interior cavity, a first end and a second end, one or more longitudinally slidable elongated magnets, one or more coils positioned exteriorly, interiorly or integrally along at least a portion of the housing, a power wire in electrical communication with the one or more coils and with the tissue stimulation device, wherein the implantable micro-generator is adapted and configured to generate energy and communicate the generated energy to the tissue stimulation device.

A method of generating power for an implantable device comprising:

• implanting a cardiac rhythm management device in a body cavity of a mammal;
• advancing a lead from the cardiac rhythm management device containing a micro-generator into at least one of an atrium and a ventricle of a mammalian heart;
• adhering the lead to an interior surface of the at least one of the atrium and the ventricle;
• wherein a magnet positioned within a housing in the micro-generator moves along an axis within the housing of the micro-generator with each heart beat;
• and further wherein energy from the movement of the magnet along an axis is transferred to the cardiac rhythm management device.

A method of generating power for an implantable device comprising:

• implanting a tissue stimulation device in a body cavity of a mammal;
• advancing an electrode from the tissue stimulation device containing a micro-generator into target mammalian tissue;
• adhering the electrode to the target mammalian tissue;
• wherein a magnet positioned within a housing in a micro-generator moves along an axis within the housing of the micro-generator in response to mammalian movement;
• and further wherein energy from the movement of the magnet along an axis is transferred to the tissue stimulation device.

A networked apparatus comprising:

• a memory;
• a processor;
• a communicator;
• a display;
• and
• an implantable cardiac rhythm management system further comprising a cardiac rhythm management device, an elongated housing adapted and configured to be positioned distally within a tip of a cardiac lead wherein the housing has an elongated interior cavity, a first end and a second end, one or more longitudinally slidable elongated magnets, one or more coils positioned exteriorly, interiorly or integrally along at least a portion of the housing, a power wire in electrical communication with the one or more coils and with an implantable medical device, wherein the implantable cardiac rhythm management system is adapted and configured to generate energy and communicate the generated energy to the implantable medical device.

A networked apparatus comprising:

• a memory;
• a processor;
• a communicator;
• a display;
• and
• a neural stimulation device comprising a power supply, an electrode, a neural stimulator connected to the power supply, the neural stimulator being adapted to generate a neural stimulation signal for delivery to the neural stimulation target through the electrode, a controller connected to the power supply, and further connected to the neural stimulator to control the neural stimulator according to a neural stimulation protocol to deliver a neural stimulation therapy, a pressure sensor electrically connected to the controller;
• and an implantable micro-generator comprising, an elongated housing adapted and configured to be positioned distally within a tip of an electrode wherein the housing has an elongated interior cavity, a first end and a second end, one or more longitudinally slidable elongated magnets, one or more coils positioned exteriorly, interiorly or integrally along at least a portion of the housing, a power wire in electrical communication with the one or more coils and with the neural stimulation device, wherein the implantable micro-generator is adapted and configured to generate energy and communicate the generated energy to the neural stimulation device.

A communication system, comprising:

• an implantable cardiac rhythm management system further comprising a cardiac rhythm management device, an elongated housing adapted and configured to be positioned distally within a tip of a cardiac lead wherein the housing has an elongated interior cavity, a first end and a second end, one or more longitudinally slidable elongated magnets, one or more coils positioned exteriorly, interiorly or integrally along at least a portion of the housing, a power wire in electrical communication with the one or more coils and with an implantable medical device, wherein the implantable cardiac rhythm management system is adapted and configured to generate energy and communicate the generated energy to the implantable medical device;
• a server computer system;
• a measurement module on the server computer system for permitting the transmission of a measurement from the implantable cardiac rhythm management system over a network;
• at least one of an API engine connected to at least one of the implantable cardiac rhythm management system and the cardiac rhythm management device to create a message about a sensed parameter and transmit the message over an API integrated network to a recipient having a predetermined recipient user name, an SMS engine connected to at least one of the implantable cardiac rhythm management system and the cardiac rhythm management device to create an SMS message about the measurement and transmit the SMS message over a network to a recipient device having a predetermined measurement recipient telephone number, and an email engine connected to at least one of the implantable cardiac rhythm management system and the cardiac rhythm management device to create an email message about the measurement and transmit the email message over the network to a recipient email having a predetermined recipient email address.

A kit for managing a cardiac rhythm comprising:

• a cardiac rhythm management device;
• one or more micro-generator devices comprising an elongated housings adapted and configured to be in communication with the cardiac rhythm management device wherein the housing has an elongated interior cavity, a first end and a second end;
• a longitudinally slidable elongated magnet having a longitudinal length greater than a cross-sectional diameter positioned within the interior cavity of the elongated housing;
• a coil along at least a portion of the housing;
• a power wire in electrical communication with the coil and with the cardiac rhythm management device;
• wherein the micro-generator is adapted and configured to generate energy and communicate the generated energy to the cardiac rhythm management device.

A lead delivery system comprising:

• a stylet wire;
• an introducer catheter dimensioned to received a cardiac lead therethrough and having an internal stylet lumen dimensioned to receive the stylet wire;
• a cardiac lead containing one or more elongated housings adapted and configured to be positioned within a distal tip of the cardiac lead wherein the housing has an elongated interior cavity, a first end and a second end;
• a longitudinally slidable elongated magnet having a longitudinal length greater than a cross-sectional diameter positioned within the interior cavity of the elongated housing;
• a coil positioned exteriorly along at least a portion of the housing;
• a power wire in electrical communication with the coil and with an implantable medical device;
• wherein the implantable micro-generator is adapted and configured to generate energy and communicate the generated energy to the implantable medical device.

A method for implanting a cardiac lead, comprising the steps of

• (a) introducing a sheath,
• (b) steering the sheath to a target location within a mammalian heart,
• (c) advancing the cardiac lead containing one or more elongated housings adapted and configured to be positioned within a distal tip of the cardiac lead wherein the housing has an elongated interior cavity, a first end and a second end;
• a longitudinally slidable elongated magnet having a longitudinal length greater than a cross-sectional diameter positioned within the interior cavity of the elongated housing;
• a coil positioned exteriorly or interiorly along at least a portion of the housing;
• a power wire in electrical communication with the coil and with an implantable medical device through a lumen of the sheath to a target location within the mammalian heart,
• (d) identifying the target location with the pacing lead,
• (e) coupling the pacing lead to cardiac tissue at the posterior summit of at least one of the left ventricular an left atrium at a first end, and
• (f) removing the sheath.