Punctal plug containing drug formulation
AssigneeJohnson & Johnson Vision Care, Inc.
InventorsNathan R. F. Beeley, Bret A. Coldren, Victor Lust
Life of this patent
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Abstract
Disclosed are lacrimal inserts and their method of use for delivery of medication to the eye. The plug includes a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of the eyelid. The plug may contain a core, or reservoir, at least partially within the body portion comprising a therapeutic agent that is configured to controlled release into the eye and is configured for release medication via a designated port, valve, or orifice in the insert housing and inhibits diffusion of medication via the housing itself.
Claims15
A lacrimal insert, comprising a housing having a first end, a second end, and a generally straight housing wall therebetween, the first end comprising a rounded or angled cross-sectional profile and the second end comprising one or more ribs, notches, protrusions, or generally annular features of greater width in cross-sectional profile than the generally straight housing wall, an inner surface wall defining a reservoir, and a drug core within the reservoir, wherein the drug comprises a therapeutic agent and the housing comprises a material that inhibits the diffusion of the therapeutic agent through the housing walls.
A lacrimal insert, comprising a housing having a first end, a second end, and a housing wall therebetween, the first end comprising a rounded or angled cross-sectional profile and the second end comprising one or more ribs, notches, protrusions, or generally annular features of greater width in cross-sectional profile than the generally straight housing wall, an inner surface wall defining a reservoir, and a drug core within the reservoir, wherein the drug comprises a therapeutic agent and the housing is comprises a material that inhibits the diffusion of the therapeutic agent through the housing walls.
Dependencies are inferred from the claim text.