System and method for monitoring blood glucose levels non-invasively
OwnerJack Amir, Itai Arad +3inventors
InventorsJack Amir, Itai Arad, Amir Ben Shalom, Gusti Aberbuch, Tsahi Asher
Life of this patent
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Abstract
A system and method is described for non-invasive monitoring of blood glucose levels. The system includes a pulse-sensor unit configured to detect a pulse wave travelling through a blood vessel and a processor unit configured to determine pulse wave velocity, to calculate the blood density and so to determine blood glucose level. Various embodiments include pulse-sensor arrays and wearable units configured to communicate with insulin pumps worn about the person of the subject.
Claims25
1-28. (canceled)
A system for non-invasive monitoring of blood glucose levels, the system comprising:
- at least one pulse-sensor unit configured to detect a pulse wave travelling through a blood vessel and a processor unit configured to receive input from said at least one pulse-sensor unit, to determine pulse wave velocity and to calculate the blood glucose level wherein said pulse-sensor unit comprises at least two sensors separated by a known spacing distance.
A method for monitoring blood glucose levels comprising the steps:
- producing a calibration curve by measuring pulse wave velocity in blood in a plurality of samples of blood having different glucose levels;
- measuring the pulse wave velocity in a blood vessel, and
- comparing the measured pulse wave velocity of said subject with said calibration curve thereby determining the blood glucose level in said subject.
A method for measuring the pulse wave velocity comprising:
- providing at least two sensors;
- collecting a set of pressure samples detected at short time intervals δt;
- selecting a first set of pressure samples from a first sensor and a second set of pressure samples from a second sensor;
- measuring the degree of correlation between said first set of pressure samples to said second set of pressure samples at a plurality of time shifts τ;
- selecting the time shift τopt with highest degree of correlation;
- determining inter-sensor spacing between said first sensor and said second sensor;
- and
- dividing the inter-sensor spacing by the optimal time shift τopt.
Dependencies are inferred from the claim text.