Phosphorylcholine group-containing compound, method of manufacturing a phosphorylcholine group-containing compound, surface-modifying agent, and a method of modifying a surface using a surface-modifying agent
AssigneeShiseido Company, Ltd.
InventorsKazuyuki MIYAZAWA, Yukimitsu Suda
Life of this patent
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Abstract
A phosphorylcholine group-containing compound that is a structure having a phosphorylcholine group represented by the following formula 1 and an amino group or a group derived from an amino group in an identical compound. (In the formula, m is 2 or more and 6 or less and p is 1 or 2. Each of X1, X2 and X3 is an alkyl group whose carbon number is 1 or more and 6 or less.)
Claims3
A method of manufacturing a phosphorylcholine group-containing compound that is a structure having a phosphorylcholine group represented by the following formula 1 and an amino group or a group derived from an amino group in an identical compound
- (In the formula, m is 2 or more and 6 or less and p is 1 or 2. Each of X1, X2 and X3 is an alkyl group whose carbon number is 1 or more and 6 or less.),
- wherein a phosphorylcholine group-containing compound in the manufacturing method is synthesized by means of an oxidative cleavage reaction of glycerophosphorylcholine to synthesize a phosphorylcholine derivative having a carboxyl group and a condensation reaction of a compound having an amino group or a group derived from an amino group and the phosphorylcholine derivative having a carboxyl group.
A method of manufacturing a phosphorylcholine group-containing compound that is a structure in which a phosphorylcholine group represented by the following formula 1 bonds to an amino group or a group derived from an amino group via a C—N linkage, an ester linkage or an amide linkage
- (In the formula, m is 2 or more and 6 or less and p is 1 or 2. Each of X1, X2 and X3 is an alkyl group whose carbon number is 1 or more and 6 or less.),
- wherein a phosphorylcholine group-containing compound in the manufacturing method is synthesized by means of an oxidative cleavage reaction of glycerophosphorylcholine to synthesize a phosphorylcholine derivative having a carboxyl group and a condensation reaction of a compound having an amino group or a group derived from an amino group and the phosphorylcholine derivative having a carboxyl group.
A method of manufacturing a phosphorylcholine group-containing compound represented by the following formula 2
- (In the formula, m is 2 or more and 6 or less and p is 1 or 2. Each of X1, X2 and X3 is an alkyl group whose carbon number is 1 or more and 6 or less. A is a secondary amine linkage, an ester linkage or an amide linkage. B is an alkyl group, a polyoxyethylene group, or an aromatic group.),
- wherein a phosphorylcholine group-containing compound in the manufacturing method is synthesized by means of an oxidative cleavage reaction of glycerophosphorylcholine to synthesize a phosphorylcholine derivative having a carboxyl group and a condensation reaction of a compound having an amino group or a group derived from an amino group and the phosphorylcholine derivative having a carboxyl group.
Dependencies are inferred from the claim text.