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US 2012/0059175 A1Published application
Synthesis of polycyclic procyanidins
AssigneeIowa State University Research Foundation, Inc.
InventorsGeorge A. Kraus, Yi Yuan
Life of this patent
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Abstract
The invention provides compounds that are A-type procyanidins. The compounds can be prepared by reacting flavylium salts with catechins or analogs thereof, for example, under anhydrous conditions in alcohol.
Claims11
A compound of Formula (D):
- wherein
- X, Y, X1, Y1, and Z1 are each individually H, OH, N(R)2, (C1-C6)alkoxy, or (C2-C6)alkanoyloxy;
- G is H, OH, (C1-C6)alkoxy, (C2-C6)alkanoyloxy, N(R)2, or NO2;
- W is H, OH, (C1-C6)alkoxy, (C1-C6)alkyl, (C1-C6)hydroxyalkyl, or (C1-C6)alkoxy-carbonyl(C1-C6)alkyl;
- each R is individually H, (C1-C4)alkyl, (C2-C6)alkanoyl, or (C6-C14)arylC(O), wherein aryl is optionally substituted with 1, 2 or 3 X;
- and
- R1 is OH or hydroxy(C1-C6)alkyl.
4 more elements
Dependencies are inferred from the claim text.