Dry powder compound formulations and uses thereof
AssigneeWyeth
InventorsSyed M. Shah, Christian Ofslager
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Abstract
The present invention provides lyophilized formulations comprising methylnaltrexone, and processes for preparation of provided formulations. Additionally provided are compositions and products containing the methylnaltrexone formulation, as well as methods for producing formulations, compositions and products. Provided formulations as well as compositions and products containing methylnaltrexone formulations are useful for preventing, treating delaying, diminishing or reducing the severity and/or incidence of side effects resulting from administration of analgesic opioids.
Claims20
An amorphous dry powder formulation consisting essentially of methylnaltrexone, or a pharmaceutically acceptable salt thereof, and a filler.
A pharmaceutical dosage preparation comprising an amorphous solid pharmaceutical formulation consisting essentially of methylnaltrexone, or a pharmaceutically acceptable salt thereof, and a filler, in a sealed container.
Dependencies are inferred from the claim text.