Drug abuse deterrent, methods and compositions
AssigneeRelevare Aust. Pty Ltd
InventorsIan Robert Chambers Cooke, Colin Stanley Goodchild, Claudia C. Gregorio-King
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Abstract
The present invention relates generally to the field of pain management. More particularly, the present invention relates to analgesic combinations of an opioid and flupirtine or retigabine which reduce the risk of substance abuse in pain management. Such combinations are referred to as abuse-deterrent fixed dose combinations (FDC).
Claims20
A method for inducing an analgesic response to pain in a subject said method comprising administering to the subject an amount of an opioid and an agent selected from flupirtine and retigabine which is effective to reduce the sensation of pain whilst reducing the enticement for substance abuse.
Use of an opioid and an agent selected from flupirtine and retigabine in the manufacture of an abuse deterrent, fixed dose composition.
An abuse deterrent, fixed dose composition comprising an opioid in an amount of from 0.1 mg to 200 mg of morphine or other opioid equivalent as determined by Table 1, and an agent selected from 25 mg to 1000 mg flupirtine and 10 mg to 500 mg retigabine.
A pain management protocol with a reduced enticement for substance abuse, said protocol comprising administering to a subject in need of pain management an amount of an opioid and an agent selected from flupirtine and retigabine which is effective to reduce the sensation of pain whilst reducing the enticement for substance abuse.
Dependencies are inferred from the claim text.