Compounds for the Treatment of Metabolic Disorders

A compound of formula (I), or a pharmaceutically acceptable salt thereof:

• p is 1 or 2;
• Z is C(O)OR4, C(O)NR4R5 or heteroaryl which may optionally be substituted by one or two groups selected from the group consisting of C1-4 alkyl, C3-6 cycloalkyl optionally substituted by C1-4 alkyl, C1-4 alkoxy, C1-4 haloalkyl and halogen;
• X is selected from the group consisting of CR6R66, O and NR7;
• Y is a C2-4 alkylene chain optionally substituted by fluoro or methyl, and when X is CR6R66 one of the carbons in the alkylene chain may be replaced by O;
• A is phenyl or a 6-membered heteroaromatic ring containing one or two nitrogen atoms;
• R1 is hydrogen, halo, cyano, C1-4 alkyl or C1-4 haloalkyl;
• q is 1 or 2;
• R2 is
• phenyl optionally substituted by one or more halo groups, or pyridyl optionally substituted by one or more halo or methyl groups;
• R3 is independently halo or methyl;
• n is 0 or 1;
• m is 0, 1 or 2;
• R4 is C2-6 alkyl or C3-6 cycloalkyl optionally substituted by C1-4 alkyl;
• R5 is hydrogen or C1-4 alkyl;
• R6 and R66 are independently hydrogen, fluoro or C1-4 alkyl;
• and
• R7 is hydrogen or C1-4 alkyl.