Anti-tumor agent containing tegafur-gimeracil-oteracil potassium combination drug and oxaliplatin
AssigneeTaiho Pharmaceutical Co., Ltd.
InventorMasakazu Fukushima
Life of this patent
Estimating the term…
Abstract
To provide a novel combination therapy which exhibits remarkable anti-tumor effect. The invention provides an anti-tumor agent comprising a combination drug containing tegafur, gimeracil and oteracil potassium, oxaliplatin, and TSU-68 or a salt thereof, in combination.
Claims14
An anti-tumor agent comprising a combination of a combination drug containing tegafur, gimeracil and oteracil potassium, oxaliplatin, and 3-[2,4-dimethyl-5-[[(Z)-2,3-dihydro-2-oxo-1H-indol-3-ylidene]methyl]-1H-pyrrol-3-yl]propanoic acid or a salt thereof.
An anti-tumor effect potentiator comprising 3-[2,4-dimethyl-5-[[(Z)-2,3-dihydro-2-oxo-1H-indol-3-ylidene]methyl]-1H-pyrrol-3-yl]propanoic acid or a salt thereof, for use in combination therapy employing a combination drug containing tegafur, gimeracil and oteracil potassium, and oxaliplatin.
Use, in combination, of a combination drug containing tegafur, gimeracil and oteracil potassium, oxaliplatin, and 3-[2,4-dimethyl-5-[[(Z)-2,3-dihydro-2-oxo-1H-indol-3-ylidene]methyl]-1H-pyrrol-3-yl]propanoic acid or a salt thereof, for the production of an anti-tumor agent.
A combination of a combination drug containing tegafur, gimeracil and oteracil potassium, oxaliplatin, and 3-[2,4-dimethyl-5-[[(Z)-2,3-dihydro-2-oxo-1H-indol-3-ylidene]methyl]-1H-pyrrol-3-yl]propanoic acid or a salt thereof, for the treatment of cancer.
A method for treatment of cancer, comprising administering, to a patient in need thereof, a combination drug containing tegafur, gimeracil and oteracil potassium, oxaliplatin, and 3-[2,4-dimethyl-5-[[(Z)-2,3-dihydro-2-oxo-1H-indol-3-ylidene]methyl]-1H-pyrrol-3-yl]propanoic acid or a salt thereof, in combination.
A method for potentiating an anti-tumor effect in a combination therapy employing a combination drug containing tegafur, gimeracil and oteracil potassium and oxaliplatin, in combination, wherein the method comprises administering, to a patient in need thereof, 3-[2,4-dimethyl-5-[[(Z)-2,3-dihydro-2-oxo-1H-indol-3-ylidene]methyl]-1H-pyrrol-3-yl]propanoic acid or a salt thereof.
3-[2,4-Dimethyl-5-[[(Z)-2,3-dihydro-2-oxo-1H-indol-3-ylidene]methyl]-1H-pyrrol-3-yl]propanoic acid or a salt thereof for use in potentiating an anti-tumor effect in a combination therapy employing a combination drug containing tegafur, gimeracil and oteracil potassium and oxaliplatin, in combination.
Dependencies are inferred from the claim text.