Methods for controlling blood-glucose levels in insulin-requiring subjects
OwnerJohn DUPREinventor
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Abstract
The present invention relates to methods of controlling blood glucose levels in subjects receiving an insulin therapy. The methods include administering to the subject receiving an insulin therapy a dipeptidyl peptidase inhibitor and a GLP-1 related peptide. The present invention relates also to the use of such a combination for treating insulin-requiring diabetes mellitus and conditions related thereto.
Claims26
A method of controlling blood glucose level in a subject receiving an insulin therapy comprising administering to the subject:
- (i) a dipeptidyl peptidase inhibitor (DPPI);
- and (ii) a glucagon-like petide-1 (GLP-1) related peptide.
A method of optimizing therapeutic efficacy for controlling blood glucose level in a subject receiving an insulin therapy comprising, comprising:
- a. establishing a dose of insulin according to insulin therapy guidelines;
- b. administering a DPPI to the subject;
- c. reducing the dose of insulin administered to the subject;
- and
- d. administering a GLP-related peptide to the subject.
Dependencies are inferred from the claim text.