Active ingredient-peptide construct for extracellular concentration
AssigneeMax-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
InventorsGunter Fischer, Miroslav Malesevic, Frank Erdmann, Jan Kühling, Michael Ilya Bukrinsky, Stephanie Constant
Life of this patent
Estimating the term…
Abstract
The present invention relates to an active ingredient-peptide construct for extracellular concentration, a process for the concentration of active ingredients in an extracellular space of a multicellular object, the use of the active ingredient-peptide construct according to the invention for the production of a medicinal product and a pharmaceutical composition containing the active ingredient-peptide construct according to the invention.
Claims34
Active ingredient-peptide construct comprising an active ingredient A and a peptide B, wherein the construct has a net charge that is negative at pH 6 and wherein the active ingredient-peptide construct is free from a constituent C which can pass through the membrane of a biological cell.
Active ingredient-peptide construct according to claim characterized in that the peptide B is not proteolytically degradable extracellularly.
Dependencies are inferred from the claim text.