Assay for the detection of recurrence in breast cancer using the novel tumor suppressor dear1
AssigneeBoard of Regents, The University of Texas System
InventorsAnn M. Killary, Steven T. Lott, Bruce G. Haffty
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Abstract
Certain aspects of the present invention relate to new diagnostic and prognostic methods involving DEAR1, a gene is located on the short arm of human chromosome 1. Specifically, analysis of expression or structure of this gene for prognosis or recurrence risk assessment is disclosed.
Claims32
An in vitro method of evaluating prognosis of a subject having cancer comprising determining if a cancer cell of the subject has a reduced level of DEAR1 expression and/or function as compared to a reference level, wherein a reduced level of DEAR1 expression and/or function indicates a poor prognosis.
Dependencies are inferred from the claim text.