Detection of biotargets using bioreceptor functionalized nanoparticles

Abstract

A system for determining a presence of biomolecule targets includes a vessel holding a sample solution suspected of containing the biomolecule targets and a plurality of probes including bioreceptor functionalized metal nanoparticles including a plurality of metal atoms. The biomolecule targets when present in the sample solution bind to the plurality of probes. A separation device is for separating the plurality of probes into a first group of probes having the biomolecule targets bound thereto and a second group of probes not having the biomolecule targets bound thereto. A reagent is introduced via a port for breaking down the metal nanoparticles in the first group or second group of probes, wherein at least one signal moiety solution is formed. A device measures a parameter of the signal moiety solution.

Dependencies are inferred from the claim text.