Defined dose therapeutic phage
AssigneeGangaGen, Inc.
InventorsJayasheela Manur, Bharathi Sriram, Sriram Padmanabhan
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Abstract
The invention provides therapeutic, defined-dose anti-bacterial phage preparations, methods to make such preparations, methods to treat bacterial infections using such preparations and methods to diagnose bacterial infections using such preparations.
Claims20
A method of reducing a bacterial population in a subject in need of treatment, said method comprising administering a therapeutically effective amount of a composition comprising an isolated phage tail that inhibits growth of a target bacterium, thereby reducing the growth of the bacterial population.
A method of treating a bacterial infection in a subject in need of such treatment, said method comprising a step of administering a therapeutically effective amount of a pharmaceutical composition comprising an isolated phage tail, wherein said isolated phage tail inhibits growth of a target bacterium, thereby treating the bacterial infection.
A method of treating a bacterial colonization in a subject experiencing colonization by a target bacterium, said method comprising administering to said subject a defined dose therapeutic anti-bacterial composition comprising an isolated phage tail, thereby treating said bacterial colonization.
The method of claim wherein said method further comprises administering a second therapeutic or antimicrobial agent.
Dependencies are inferred from the claim text.