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US 2012/0058196 A1Published application
Pharmaceutical compositions of dextran polymer derivatives and a carrier material
AssigneeBend Research, Inc.
InventorsDwayne T. Friesen, David T. Vodak
Life of this patent
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Abstract
Pharmaceutical compositions are provided comprising (a) nanoparticles of an active agent and a dextran polymer derivative, and (b) a carrier material.
Claims20
A pharmaceutical composition comprising:
- (a) nanoparticles comprising an active agent and a dextran polymer derivative, said nanoparticles having an average size of less than 1000 nm;
- and
- (b) a carrier material;
- wherein said carrier material constitutes from 5 wt % to 99 wt % of the combined mass of (1) said nanoparticles and (2) said carrier material, and said dextran polymer derivative is selected from dextran acetate, dextran propionate, dextran succinate, dextran acetate propionate, dextran acetate succinate, dextran propionate succinate, dextran acetate propionate succinate, and mixtures thereof.
1 more element
A composition suitable for inhalation, comprising a plurality of particles, each of said particles comprising:
- (a) nanoparticles comprising an active agent and a dextran polymer derivative, said nanoparticles having an average size of less than 1000 nm;
- and
- (b) a carrier material;
- wherein said carrier material constitutes from 5 wt % to 99 wt % of the combined mass of (1) said nanoparticles and (2) said carrier material;
- wherein said dextran polymer derivative is selected from dextran acetate, dextran propionate, dextran succinate, dextran acetate propionate, dextran acetate succinate, dextran propionate succinate, dextran acetate propionate succinate, and mixtures thereof;
- and
- said particles have a mass median aerodynamic diameter of 0.5 to 100 μm.
4 more elements
Dependencies are inferred from the claim text.