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US 2012/0058188 A1Published application
Lipid encapsulated interfering rna
AssigneeProtiva Biotherapeutics, Inc.
InventorsIan MacLachlan, Ellen Grace Ambegia, James Heyes
Life of this patent
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Abstract
The present invention provides compositions and methods for silencing gene expression by delivering nucleic acid-lipid particles comprising a siRNA molecule to a cell.
Claims19
1-51. (canceled)
A nucleic acid-lipid particle, said nucleic acid-lipid particle comprising:
- an interfering RNA;
- a cationic lipid;
- a non-cationic lipid;
- and
- a conjugated lipid that inhibits aggregation of particles.
2 more elements
Dependencies are inferred from the claim text.