Plant extracts for use in brain modulation
AssigneeIntermed Discovery GmbH
InventorsErnst Roemer, Torsten Grothe
Life of this patent
Estimating the term…
Abstract
Compounds obtainable from plants, e.g. of the genus Eucalyptus, or from microorganisms are shown to be useful as CNS activity modulators useful e.g. in the treatment of depression, for lifting mood and/or for increasing behavioural initiative and the like. This use and related aspects form embodiments of the invention. Also compounds as such are presented. The compounds useful are acylphloroglucine derivatives of the formula I, wherein the substituents are as defined in the description.
Claims13
A method of treatment comprising:
- providing a compound or mixture of compounds selected from the group consisting of Eucalyptone, Macrocarpal A, or an ester or esters of Eucalyptone, an ester or esters of Macrocarpal A, a salt or salts of Eucalyptone, and a salt or salts of Macrocarpal A, and administering a therapeutically effective amount of the compound or mixture of compounds to a patient in need thereof for one or more of prophylactically and/or therapeutically lifting the mood, increasing cognitive performance, or positively affecting motivation.
A functional food product comprising a compound or a mixture of compounds selected from the group consisting of Eucalyptone, and Macrocarpal A, or an ester or esters of Eucalyptone, an ester or esters of Macrocarpal A, a salt or salts of Eucalyptone, and a salt or salts of Macrocarpal A, as active ingredient together with a pharmaceutically acceptable diluent or carrier for mood-lifting in healthy persons or one or more of the treatment or prophylaxis of one or more of the following symptoms or disorders:
- anxiety, memory deficits and dysfunctions, lack of concentration, diminished emotional well-being, low spirits, or lack of appetite, wherein the functional food product comprises 0.001 to 50% by weight of Eucalyptone, Macrocarpal A, or a mixture of Eucalyptone and Macrocarpal A.
A pharmaceutical composition, nutraceutical composition or functional food product comprising a compound or a mixture of compounds selected from the group consisting of Eucalyptone, Macrocarpal A, an ester or esters of Eucalyptone, an ester or esters of Macrocarpal A, a salt or salts of Eucalyptone, and a salt or salts of Macrocarpal A, as active ingredient together with a pharmaceutically acceptable diluent or carrier for mood-lifting in healthy persons or one or more of the treatment or prophylaxis of one or more of the following symptoms or disorders:
- anxiety, memory deficits and dysfunctions, lack of concentration, diminished emotional well-being, low spirits, or lack of appetite,
- wherein the share of Eucalyptone, Macrocarpal A, or a mixture of Eucalyptone and Macrocarpal A, is in the range from 0.01 to 30% by weight.
Dependencies are inferred from the claim text.